FDA Labeled Drugs

Medications with FDA Genetic Warnings

Genetic factors influence the metabolism and transport of thousands of drugs. The drugs listed below are required by the U.S. Food and Drug Administration (FDA) to provide specific pharmacogenetic information on their package inserts, because of their known potential for adverse effects. The drug labeling describes drug exposure and clinical response variability; adverse event risk; genotype-specific dosing; mechanisms of drug action; and polymorphic drug target and disposition genes.

This list is regularly updated. If you are concerned about a medication not on this list, please call and talk with one of our DNA Testing Consultants at 800-TEST-DNA (800-837-8362).

List of PGx labeled drugsMost common brand nameEnzyme
amitriptylineElavilCYP2D6
aripiprazoleAbilifyCYP2D6
atomoxetineStratteraCYP2D6
carisoprodolSomaCYP2C19
carvedilolCoregCYP2D6
celecoxibCelebrexCYP2C9
cevimelineEvoxacCYP2D6
citalopramCelexaCYP2C19
clobazamOnfiCYP2C19
clomipramineAnafranilCYP2D6
clopidogrelPlavixCYP2C19
clozapineClozarilCYP2D6
codeineTylenol #3CYP2D6
desipramineNorpraminCYP2D6
dexlansoprazoleDexilantCYP2C19
diazepamValiumCYP2C19
doxepinSinequanCYP2D6
esomeprazoleNexiumCYP2C19
flurbiprofenAnsaidCYP2C9
fluvoxamineLuvoxCYP2D6
galantamineRazadyneCYP2D6
iloperidoneFanaptCYP2D6
imipramineTofranilCYP2D6
metoprololLopressorCYP2D6
modafinilProvigilCYP2D6
nortriptylinePamelorCYP2D6
pantoprazoleProtonixCYP2C19
perphenazineTrilafonCYP2D6
propafenoneRythmolCYP2D6
protriptylineVivactilCYP2D6
quinidine/dextromethorphanNuedextaCYP2D6
rabeprazoleAciphexCYP2C19
risperidoneRisperdalCYP2D6
tetrabenazineXenazineCYP2D6
thioridazineMellarilCYP2D6
tolterodineDetrolCYP2D6
tramadolUltramCYP2D6
warfarinCoumadinCYP2C9